The four volume set LNCS 9489, LNCS 9490, LNCS 9491, and LNCS 9492 constitutes the proceedings of the 22nd International Conference on Neural Information Processing, ICONIP 2015, held in Istanbul, Turkey, in November 2015. The 231 full papers presented were carefully reviewed and selected from 375 submissions. The 4 volumes represent topical sections containing articles on Learning Algorithms and Classification Systems; Artificial Intelligence and Neural Networks: Theory, Design, and Applications; Image and Signal Processing; and Intelligent Social Networks.