1. The Neurobiology of Developmental Disorders -- 1. Introduction -- 2. Neurobiology of Brain Development -- 3. Mammalian Developmental Neuropathology -- 4. Conclusion to Sections 2 and 3 -- 5. Biological Basis of Autism -- 6. Conclusions -- 7. References -- 2. Child Psychiatric Epidemiology: Implications for Clinical Research and Practice -- 1. Introduction -- 2. What Is Epidemiology? -- 3. Assessing Child Psychopathology: The Two Traditions in Epidemiology -- 4. Recent Developments in Child Psychiatric Epidemiology -- 5. Applications to Clinical Research and Practice -- 6. Summary and Conclusions -- 7. References -- 3. Recent Developments in High Risk Research -- 1. The High Risk Paradigm -- 2. Studies of the Children of Schizophrenics -- 3. Possible Limitations of the Studies of Children of Schizophrenics -- 4. Alternative Methods for Identifying Individuals Potentially at Risk for Schizophrenia -- 5. Individuals at Risk for Other Psychiatric Disorders -- 6. Differentiation of Outcome among Offspring of Parents with Different Psychiatric Diagnoses -- 7. Implications of High Risk Studies for Intervention -- 8. Conclusions -- 9. References -- 4. Cognitive Approaches to Depression in Children: Current Findings and New Directions -- 1. Depressive Cognitions in Children -- 2. Beck's Information-Processing Model -- 3. Depressive Attributional Style -- 4. Self-Control Cognitions -- 5. Conclusions and Limitations in Research on Children's Depressive Cognitions -- 6. Clinical Implications -- 7. Conclusion -- 8. References -- 5. Thought Disorder in the Childhood Psychoses -- 1. Introduction -- 2. Historical Overview -- 3. Development of Instruments for the Measurement of Formal Thought Disorder in Children -- 4. Studies on the K-FTDS -- 5. Reliability of the K-FTDS -- 6. Effectiveness of the Story Game Procedure -- 7. Diagnostic Validity of the K-FTDS -- 8. Implications for Future Research -- 9. References -- 6. Convergence of Approaches in Localizing the Hyperactivity Deficit -- 1. Introduction -- 2. The Development of a Model -- 3. Energetic Model -- 4. Vigilance and Hyperactivity -- 5. AFM, Drugs, and Event-Related Potentials -- 6. Discussion -- 7. References -- 7. Adolescent Pregnancy and Early Sexual Onset -- 1. Introduction -- 2. Consequences of Adolescent Conception -- 3. Influences on Age at First Coitus -- 4. Early Sexual Behavior -- 5. Intervention and Prevention -- 6. References -- 8. Advancing Knowledge about the Onset of Delinquency and Crime -- 1. The Importance of Onset -- 2. Theoretical and Conceptual Issues -- 3. What Is Known about Onset? -- 4. Possible Influences on Onset -- 5. Experimental Interventions -- 6. How Can Knowledge Be Advanced? -- 7. Summary and Conclusions -- 8. References -- 9. The Effects of Craniofacial Deformity, Chronic Illness, and Physical Handicaps on Patient and Familial Adjustment: Research and Clinical Perspectives -- 1. Introduction -- 2. Facial Deformity, Attractiveness, and Social Interaction -- 3. Developmental Risks to Craniofacially Deformed Patients -- 4. Conceptual and Methodological Issues -- 5. Clinical Implications of Research on Children with Craniofacial Deformities and Other Handicaps -- 6. References -- 10. Adjustment to Serious Childhood Illness -- 1. Introduction -- 2. Childhood Cancer -- 3. Sickle-Cell Disease -- 4. Psychological Adjustment and Illness -- 5. Factors Affecting the Risk of Dysfunction -- 6. Issues in Clinical Assessment -- 7. Conclusion -- 8. References.