Cover image for The unfolded protein response and cellular stress. Part C
The unfolded protein response and cellular stress. Part C
Title:
The unfolded protein response and cellular stress. Part C
Publication Information New:
Amsterdam [Netherlands] ; Boston [Mass.] : Elsevier/Academic Press, 2011.
Physical Description:
1 online resource (xlix, 407 pages) : illustrations
Series:
Methods in enzymology, v. 491

Methods in enzymology ; v. 491.
Contents:
CFTR expression regulation by the unfolded protein response -- GRP78/BIP modulation of GRP78/BIP in altering sensitivity to chemotherapy -- Targeting the unfolded protein response in cancer therapy -- Large-scale analysis of UPR-mediated apoptosis in human cells -- Quantitative analysis of amino acid oxidation markers by tandem mass spectrometry -- Animal models in the study of the unfolded protein response -- Measurement of fluoride-induced endoplasmic reticulum stress using Gaussia luciferase -- Analysis of nelfinavir-induced endoplasmic reticulum stress -- Using temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo -- Glycoprotein maturation and the UPR -- Monitoring and manipulating mammalian unfolded protein response -- A screen for mutants requiring activation of the unfolded protein response for viability -- Signaling pathways of proteostasis network unrevealed by proteomic approaches on the understanding of misfolded protein rescue -- Decreased secretion and unfolded protein response UP regulation -- Measuring signaling by the unfolded protein response -- Quantitative measurement of events in the mammalian unfolded protein response -- Regulation of immunoglobulin synthesis, modification, and trafficking by the unfolded protein response a quantitative approach -- Use of chemical genomics in assessment of the UPR -- Small GTPase signaling and the unfolded protein response -- Inhibitors of advanced glycation and endoplasmic reticulum stress.
Abstract:
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
Local Note:
Elsevier
Added Author:
Added Corporate Author:

Language:
English