Unusual suspects in the twilight zone between the Hsp90 interactome and carcinogenesis / Evangelia Vartholomaiou, Pablo C. Echeverría and Didier Picard -- Impact of posttranslational modifications on the anticancer activity of Hsp90 inhibitors / Mark R. Woodford, Diana Dunn, Jonelle B. Miller, Sami Jamal, Len Neckers and Mehdi Mollapour -- Anticancer inhibitors of Hsp90 function: beyond the usual suspects / Gaurav Garg, Anuj Khandelwal and Brian S. J. Blagg -- HSP90 in cancer: transcriptional roles in the nucleus / Stuart K. Calderwood and Len Neckers -- Hsp90 as a 'chaperone' of the epigenome: insights and opportunities for cancer therapy / Jennifer S. Isaacs -- Emerging roles of extracellular Hsp90 in cancer / Daniel Senh Wong and Daniel G. Jay -- GRP94/gp96 in cancer: biology, structure, immunology and drug development / Bill X Wu, Feng Hong, Yongliang Zhang, Ephraim Ansa-Addo and Zihai Li -- HSP90 and immune modulation in cancer / Michael W. Graner -- Hsp90: a global regulator of the genotype-to-phenotype map in cancers / Daniel Jarosz.