This book reports on the current state of human computer interaction (HCI) in biomedicine and healthcare, focusing on the cognitive underpinnings of human interactions with people and technology. Drawing from the current research in HCI, this book addresses key theories, models and evaluation frameworks, and their application in biomedical contexts. Health information technologies have become increasingly vital tools for the practice of clinical medicine. However, numerous challenges remain in order to fully realize their potential as instruments for advancing clinical care and enhancing patient safety. Cognitive Informatics for Biomedicine: Human Computer Interaction in Healthcare is indispensable to those who want to ensure that the systems they build, and the interactive environments that they promote, will reflect the rigor and dedication to human-computer interaction principles that will ultimately enhance both the user's experience and the quality and safety of the care that is offered to patients.