New Approaches to Supply Chain Modeling -- Classification and clustering of clients of a company dedicated to the distribution of auto parts in the metropolitan area of Monterrey -- Guide for sustainable project analysis to improve energy efficiency of Mexican SME -- A multi-product stochastic programming model for sup-plier selection in a humanitarian relief chain -- Image Classification Applied to the Detection of Leather Defects for Smart Manufacturing Suppliers analysis and selection to improve supply chain performance -- Feasibility Analysis of a Supply Chain for Castor Oil Biodiesel Distribution in Central Mexico -- Automation of storage and distribution terminals: The case of logistics operators -- Health Systems: Strategies for the delimitation of vulnerable areas and identification of failures of medical equipment -- Hub location problem for medical care during epidemic outbreaks -- Application of Spectral Cluster for the detection of high priority areas of attention for COVID-19 in Mexico -- Identifying the Main Causes of Medical Devices Failures while Surgery at High Specialization Hospital implementing Lean Six Sigma -- Applied optimization -- MTGWA: a multithreaded Gray Wolf algorithm with strategies based on Simulated Annealing and Genetic Algorithms -- Effectiveness of some tests of spatial randomness in the detection of weak graphical passwords in Passpoint -- Analysis of the number of sides of Voronoi polygons in PassPoint -- Modeling Nanocomposites with Ellipsoidal and Conical Inclusions by Optimized Packing -- Applications in the education sector -- Design strategies for university educational supply chain -- Teaching of TCP Fundamental Operations using a Digital Tool.