Regulation of IP3 Receptors by IP3 and CA2+ -- The Endoplasmic Reticulum: a Central Player in Cell Signalling and Protein Synthesis -- Mitochondrial and ER Calcium Uptake and Release Fluxes and Their Interplay in Intact Nerve Cells -- Global and Local Regulation of Neuronal Differentiation By Calcium Transients -- Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling -- Models of Cardiac CA2+- Induced CA 2+ Release and Ca2+ Sparks -- From Simple to Complex Ca2+ Oscillations: Regulatory Mechanisms and Theoretical Models -- Information Processing in Calcium Signal Transduction -- Modeling Calcium Waves -- Mathematical Modeling and High Resolution Fluorescence Imaging for Studying Calcium Regulation -- Langevin Modeling of Intracellular Calcium Dynamics -- Building a Wave - Models of the Puff-to-Wave Transition.