Fasten your seat belts, 'cause two of Hollywood's hottest women are revving it up and taking it on the road. When unhappy housewife Thelma and her wise cracking waitress friend Louise decide to take a break from their lives, Thelma from her chauvinistic husband and Louise from her commitment shy musician boyfriend, they embark on a trip that leads to a tragic incident at a roadside honky tonk. In an instant, their weekend getaway becomes just that as they flee across the American southwest with the police a step behind.