Half Title; Editorial Board; Advances in QUANTUM CHEMISTRY; Copyright; Contents; Preface; Contributors; Chapter One Stochastics of Energy Loss and Biological Effects of Heavy Ions in Radiation Therapy; 1. Introduction; 2. Energy loss at macroscopic level; 2.1 Continuous transport of particles through matter: Classical approach; 2.2 Convolutions for range straggling; 2.3 Straggling in thin segments; 2.4 Monte Carlo methods; 3. Bragg functions; 3.1 Nuclear interactions; 3.2 Practical details for protons; 3.3 Practical details for C-ions; 4. Energy loss and deposition at microscopic levels

4.1 Energy loss4.2 Energy deposition; 4.3 Energy deposition in microscopic volumes; 5. Stochastics of energy loss in cells; 5.1 General features; 5.2 MC simulation of stochastics at the Bragg peak; 5.2.1 Simulation of random number nj of ions traversing cell j; 5.2.2 Energy deposition z in cells; 6. Bio-effects; 7. Conclusions; Acknowledgments; References; Chapter Two On the Accuracy of Stopping Power Codes and Ion Ranges Used for Hadron Therapy; 1. Introduction; 2. Tables and programs; 3. Liquid water as a target; 3.1 Stopping power of water for hydrogen ions

3.2 Range measurements for water, and mean ionization energy4. Other target substances and statistical comparisons; 4.1 Statistical comparisons for H and He ions; 4.2 Application to therapy using H ions; 4.3 Statistical comparisons for carbon ions; 5. Conclusions; 6. List of acronyms; References; Chapter Three On the Determination of the Mean Excitation Energy of Water; 1. Introduction; 2. Some basic theory; 3. Theoretical determination of I0; 4. Experimental determination of I0; 5. Conclusion; Acknowledgments; References

Chapter Four Molecular Scale Simulation of Ionizing Particles Tracks for Radiobiology and Hadrontherapy Studies1. Introduction; 2. Detailed step by step track structure codes; 2.1 Monte-Carlo codes; 2.2 Collision processes: cross sections; 2.3 Sub excitation electrons and the chemical phase; 3. Radiation microdosimetry analysis; 3.1 Theoretical and experimental microdosimetry; 3.2 Ions RBE estimation; 4. DNA damage estimation; 4.1 Track structure detailed approach; 4.2 Stewart and Semenenko MCDS method; 4.3 Garty statistical approach; 4.4 DBSCAN clustering estimation; 5. Conclusion

AcknowledgmentsReferences; Chapter Five Verifying Radiation Treatment in Proton Therapy via PET Imaging of the Induced Positron-Emitters; 1. Introduction; 2. Positron emitter production; 3. Nuclear reaction cross sections; 4. Monte Carlo simulations; 5. Results; 6. Discussion and conclusions; ACKNOWLEDGMENTs; References; Chapter six Inelastic Collisions of Energetic Protons in Biological Media; 1. Introduction; 2. Dielectric formalism for inelastic scattering; 2.1 Projectile description: electronic charge density; 2.2 Target description: electronic excitation spectrum