pt. 1. Theory. The institutional nature of ICT and organizational change ; The socio-technical nature of information systems innovation ; Multiple situated rationalities ; The global, the local, and the disembedded -- pt. 2. Insights from case studies. Pemex- transforming a national company ; IKA- striving to modernize a state bureaucracy ; An experiment of flexible specialization in Cyprus ; Medical drug utilization information systems in the United States and Europe ; The nature and significance of global diversity for information systems.