Dünyanın en iyi dolandırıcıları olan Bloom kardeşler, milyonerleri birbirinden değişik senaryolarla dolandırmakla geçinirler. Her filmdeki gibi Bloom, Stephan ve sessiz ortakları Bang-Bang son işlerini yapmak adına biraraya gelir. Son işleri ise zengin ve güzel olan Penelope’yi çıkardıkları dünya turunda dolandırıp $2.5 dolar koparmaktır. Ancak Bloom’un Penolope’ye aşık olması nedeniyle işler yolunda gitmez. Avcılar ava dönüşür.

Stephen and Bloom are brothers who have been con artists since they were kids. Stephen is the mastermind, while Bloom is the main character of Stephen’s stories. As adults, they travel the world and never enlist the same people twice in their cons, except for their consistent sidekick, the mysterious and primarily silent Bang Bang, a Japanese woman who just appeared in their lives one day and happens to have a penchant for blowing things up. As Bloom hits his mid-thirties, he wants to quit the business. Stephen talks him into one last con. The mark is the eccentric, lonely but beautiful New Jersey heiress, Penelope Stamp. As the brothers go through their final con on Penelope, three main problems may occur to thwart the plan. First, the brothers’ former mentor and now arch enemy, Diamond Dog, may exact his long awaited revenge; second, Penelope may end up being more unpredictable than all their former marks; and third, Bloom, who has let love slip by in his life, may fall for Penelope. But through the process, no one ever really knows who is conning whom.