The growing number of older adults in the United States poses a significant challenge to families, healthcare systems, mental health services, and many other caregiving groups. Using the Grand Challenges for Social Work initiative as a framework, this text evaluates critical policies and issues pertaining to older adults, identifying both the overall systemic inequalities currently working against older adults as well as specific areas that require updated policies and interventions. It calls for active attention to the implementation of science-based research, policy, and practices to promote health and well-being. Among the topics addressed: Family violence against older adults Disaster planning and preparedness Building financial capability for aging families Health needs of incarcerated older adults Closing the gap in healthcare services for older adults Social isolation and its effects on mental health and well-being A useful gerontology resource for students, social work scholars, and practitioners, Gerontological Social Work and the Grand Challenges advocates for justice and equal opportunity for older adults, and highlights important social issues that must be urgently addressed in the near future.