Preface -- Mitochondrion: A novel center for cancer cell signalling -- Exploiting BH3 mimetics for cancer therapy -- Regulation of mitochondrial function by MicroRNA -- Mitochondrial complex II as a target for anti-cancer drugs -- Exploiting celecoxib in cancer therapy -- Activation of mitochondria-driven pathways by artemisinin and its derivatives -- Vitamin E analogues as prototypic mitochondria-targeting anti-cancer agents -- Targeting mitochondria of cancer cells: Mechanism and compounds -- Targets and strategies for the mitochondrial assault on cancer -- Emerging anti-cancer targets in mitochondria -- Relevance of mitochondrial functions and plasticity in tumor biology -- Crosstalk between p53 and mitochondrial metabolism -- Progression of cardiomyopathy in Friedreich's ataxia, a mitochondrial disease -- Index.