Preface -- Use of Mass Spectrometry to Study the Centromere and Kinetochore -- Critical Foundation of the Kinetochore: the Constitutive Centromere Associated Network (CCAN) -- The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function -- Centrochromatin of Fungi -- Evolutionary Lessons from Species with Unique Kinetochores.-Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis -- Orchestrating the Specific Assembly of Centromeric Nucleosomes -- Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishment -- Post-translational Modifications of Centromeric Chromatin -- Centromere Silencing Mechanisms -- Centromere Transcription: Means and Motive -- The Promises and Challenges of Genomic Studies of Human Centromeres -- DNA Sequences in Centromere Formation and Function -- The Unique DNA Sequences Underlying Equine Centromeres -- Centromere Dynamics in Male and Female Germ Cells -- Cell Biology of Cheating-Transmission of Centromeres and Other Selfish Elements Through Asymmetric Meiosis -- Biophysics of Microtubule End Coupling at the Kinetochore -- Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing -- A Kinase-Phosphatase Network That Regulates Kinetochore-Microtubule Attachments and the SAC -- Centromeric Cohesion: Molecular Glue and Much More -- Centromere Structure and Function -- The Role of Centromere Defects in Cancer.