This book addresses the molecular biology of noroviruses (NoVs), pathogenesis, viral diversity and its impact on selective pressure, host susceptibility and outbreaks, clinical diagnosis, and the latest advances in the management and treatment of disease caused by NoVs. It offers a detailed analysis of our current understanding of the innate and the adaptive immune responses stimulated by NoVs, and discusses the complexity of the ongoing vaccine development and the urgent need for specific immune correlates of protection to advance the field. This is the first book on noroviruses. Written by leading specialists, it is essential reading for virologists and immunologists.