Introduction: Enhancing Detection and Early Cancer Recognition with Multimodal Optical Imaging and Spectral Analysis -- Malignant tissue optics -- Optical clearing of biological tissues: prospects of application for multimodal cancer diagnostics -- Multiparametric analysis of tumor using microscopic fluorescence imaging -- NIRS for brain cancer detection -- Exhaled air analysis using wideband wave number tuning range infrared laser photoacoustic spectroscopy -- Multispectral and multimodal fiber sensing in oncology -- Diagnostics of pigmented skin tumors based on laser-induced autofluorescence and diffuse reflectance spectroscopy -- Raman-based molecular imaging and analytics, Surface-enhanced Raman spectroscopy for cancer diagnostics, Raman/CARS/TPEF/SHG multimodal imaging as a pathological screening tool -- In vivo Multimodal Optical Biopsy of Skin Cancer -- Raman hyperspectroscopy and advanced statistics for cancer differentiation -- Intraoperative brain cancer detection with Label-Free Multimodal Optical Spectroscopy -- 3D confocal Raman and two-photon microscopy imaging of the skin -- Multimodal Optical Imaging for Cancer Detection -- Multidimentional and Multilevel Imaging: towards 3D histopathology -- Multimodal OCT for malignancy imaging -- Multimodal texture analysis of OCT tumor images -- Hyperspectral imaging and cancer detection -- Multimodal Deep Imaging using SORS and OCT: for precise cancer boundary detection -- FLIM imaging combined with MRI -- Terahertz spectroscopy of human brain tumor.