This book discusses the main techniques and newest trends to manage and optimize the production and service systems. The book begins by examining the three main levels of decision systems in production: the long term (strategic), the middle term (tactical) and short term (operational). It also considers online management as a new level (a sub level of the short term). As each level encounters specific problems, appropriate approaches to deal with these are introduced and explained. These problems include the line design, the line balancing optimization, the physical layout of the production or service system, the forecasting optimization, the inventory management, the scheduling etc. Metaheuristics for Production Systems then explores logistic optimization from two different perspectives: internal (production management), addressing issues of scheduling, layout and line designs, and external (supply chain management) focusing on transportation optimization, supply chain evaluation, and location of production. The book also looks at NP-hard problems that are common in production management. These complex configurations may mean that optimal solutions may not be reached due to variables, but the authors help provide a good solution for such problems. The effective new results and solutions offered in this book should appeal to researchers, managers, and engineers in the production and service industries.