Machine Intelligence is changing every aspect of our lives. Internet traffic and sensors in households, cars, and wearables provide data that oligopolistic companies collect and use to extract patterns of human behavior. Further, active digital assistants are taking over more and more of our everyday decisions. Humanity is on the verge of an evolutionary leap and it is time to determine if this development will benefit people's wellbeing or will just mean the accumulation of capital and power with no regard for quality of life. This book integrates the perspectives of various disciplines that are striving to establish resilient foundations - computer science, economics and social sciences, political science, psychology, philosophy, neuroscience, ethics and religion - in order to clarify a number of positions and, as a result, objectify the discussions. Written by Hubert Osterle, a researcher working at the interface of these disciplines, the book promotes debate on the future of man and machine, on happiness and evolution and on the major changes brought about by digital technology. Last but not least, it is a manifesto calling for a new - integrated - discipline to be founded: life engineering.