This volume presents the proceedings of the13th International Conference on Biomedical Engineering (ICBME2008), help from the 3rd to 6th December 2008 in Singapore. The presented papers reflect the broad scope of the conference including topics like: Artificial Organs, Bioengineering Education, Bioinformatics & Digital Medicine, Biomaterials, Biomechanics, Biomedical Imaging, Biomedical Instrumentation, Biosensors, BioMEMs & Lab-on-Chip, Biosignal Processing, Cardiovascular Bioengineering, Cell & Biomolecular Mechanics, Cellular & Biomolecular Engineering, Clinical Engineering, Computational Bioengineering, Computer-Integrated & Computer-Assisted Surgery, Controlled Drug Delivery, Mechanobiology, Medical Robotics, Micro Nano Biomedical devices & systems, Nanobiotechnology, Neural Systems Engineering, Orthopaedics, Prosthetics & Orthotics, Rehabilitation Engineering & Assistive Technology, Pharmaceutical Sciences & Engineering, Physiological System Modeling, Regenerative Medicine & Tissue Engineering, Telemedicine & Healthcare.