Part I. Considerations in Device Development -- 1. Schlemm's Canal And Collector Channels As Therapeutic Targets -- 2. Intraoperative Assessment of the Conventional Collector Outflow System As Therapeutic Target -- 3. Suprachoroidal Space As A Therapeutic Target -- 4. Ciliary Body as a Therapeutic Target -- 5. Clinical Trials for IOP lowering Devices to Support a FDA Premarket Submission -- 6. Considerations in Patenting New Surgical Devices for Glaucoma: The Changing Patent Law Landscape -- Part II. Laser Technologies -- 7. New Laser Technologies -- 8. Excimer Laser Trabeculostomy (ELT) - an effective MIGS procedure for Open Angle Glaucoma -- 9. Laser Therapies: Cyclodestructive Procedures -- 10. CO2 Laser-Assisted Deep Sclerectomy -- Part III. Ultrasound Technologies -- 11. Ultrasonic Circular Cyclo-Coagulation -- 12. TUG (Therapeutic Ultrasound for Glaucoma) -- Part IV. Internal Outflow Enhancement -- 13. The iStent® MIGS Family: iStent®, iStent Inject®, and iStent Supra® -- 14. Canaloplasty -- 15. The Hydrus Micro-Stent -- 16. Minimally Invasive Glaucoma Surgery: Trabeculectomy ab interno -- Part V. External Outflow Enhancement -- 17. XEN Glaucoma Implant. The solution designed by Aquesys® -- 18. Glaucoma Surgery With the Ex-Press Glaucoma Shunt -- 19. Molteno Developments in Traditional Outflow Implants -- 20. Ahmed Glaucoma Valve Model M4 -- Part VI. Suprachoroidal Outflow Devices -- 21. The CyPass Suprachoroidal Micro-Stent -- 22. STARfloTM: a suprachoroidal drainage implant made from STAR® Biomaterial -- 23. SOLX Suprachoroidal Shunt -- Part VII. Cataract Surgery -- 24. Cataract surgery: The 'new' glaucoma procedure? -- 25. Lens Extraction For Angle Closure Glaucoma -- Part VIII. Future Developments -- 26. Adopting New Surgical Methods: How I do it & How I Choose: Going with the Flow -- 27. Biomarkers to predict glaucoma surgical success.