1. The panic disorder concept: a historical perspective -- 2. A neural systems approach to the study of panic disorder -- 3. The hippocampus and Panic Disorder: evidence from animal and human studies -- 4. Panic Disorder, is it really a mental disorder? From body functions to the homeostatic brain -- 5. Staging of panic disorder: implications for neurobiology and treatment -- 6. Panic disorder respiratory subtype -- 7. Lifelong opioidergic vulnerability through early life separation: A recent extension of the false suffocation alarm theory of panic disorder -- 8. Circadian Rhythm in Panic Disorder -- 9. Some genetic aspects of panic disorder -- 10. Panic disorder and personality disorders -- 11. Possible mechanisms linking panic disorder and cardiac syndromes -- 12. Panic disorder and cardiovascular death: what's beneath? -- 13. Pulmonary embolism in the setting of panic attacks -- 14. Panic and Self-consciousness -- 15. Pharmacological treatment with the Serotonin Selective Receptores inhibitors -- 16. Benzodiazepines in panic disorder -- 17. Repetitive transcranial magnetic stimulation to treat panic disorder -- 18. Exercise in Panic Disorder: implications for maintenance, treatment and physical health -- 19. Pharmacological treatment of panic disorder with non-selective drugs.