Part I: Introduction to Recurrent Pregnancy Loss -- Recurrent pregnancy loss: definitions, epidemiology, and prognosis -- Implantation, Physiology of Placentation -- Part II: Causes of Recurrent Pregnancy Loss -- Endocrine abnormalities in RPL -- Genetics of recurrent pregnancy loss -- Inherited and Acquired Thrombophilias and Adverse Pregnancy Outcomes -- Immunological causes of recurrent pregnancy loss -- Anatomical aspects in recurrent pregnancy loss -- Male Factors in Recurrent Pregnancy Loss -- Lifestyle and RPL -- The common characteristics between Infertility and recurrent pregnancy loss -- Part III: Management of Recurrent Pregnancy Loss. Contemporary Prevention and treatment of recurrent pregnancy loss -- Part IV: Psychological and Supporting Aspects of Recurrent Pregnancy Loss -- The healthcare giver's perspective - The importance of emotional support for women with recurrent RPL -- A Patient's Perspective -- Part V: The Future -- New Frontiers in RPL research and treatment.