History of pineal gland as neuroendocrine organ and discovery of melatonin -- Bibliometric study of scientific research on melatonin during the last 25 years -- Neuroimaging of the pineal gland. Focus on Primary Insomnia -- Melatonin: Basic and clinical aspects -- Melatonin and melatonin receptors in neuroprotection -- Melatonin supplementation in neurodegenerative diseases: Current status -- Therapeutic potential of melatonin in combination with other drugs against neurodegeneration -- Melatonin, a neuroprotective agent: relevance for stress induced neuropsychiatric disorders -- Melatonin, sleep, circadian rhythm and mood disorders -- Melatonin induces antidepressant-like behavior by promotion of hippocampal neurogenesis -- Association between melatonin and neuroimmune diseases -- Melatonin in clinical states of patients with fibromyalgia syndrome -- Melatonin's beneficial effects in hepatic injury -- Melatonin as a novel therapeutic agent against chemical warfare agents -- New galenic formulations of melatonin -- Melatonergic drug ramelteon in neurotherapeutics -- Melatonergic antidepressant agomelatine and its efficacy in depressive disorders -- Agomelatine, melatonin and depression -- Neuropsychological models of depression -- Chronobiology of mood disorders -- Bipolar disorders and biological rhythm -- Circadian clock genes and mood disorders -- Understanding the biologically adaptive side of mood disorders: a focus on affective temperaments -- Sleep abnormalities as diagnostic tool for major depressive disorder -- Depression: Correlations with thyroid hormones in major depressive disorder -- History of the discovery of antidepressant drugs -- Neurocognitive deficit in bipolar disorders -- Combination strategies in treatment-resistant depression -- Antidepressant drugs in elderly -- Antidepressant efficacy of escitalopram in major depressive disorder -- Antidepressant medications and suicide risk: What was the impact of FDA warning? -- Neurobiology and pharmacological prevention of suicide in mood disorders -- Antidepressants and anticonvulsants as adjuvant analgesics in chronic pain -- Genetic polymorphisms of cytochrome P450 enzymes and antidepressants -- Pharmacogenomics of antidepressant drugs -- Antidepressants modulate microglia beyond the neurotransmitters doctrine of mood disorders -- Brain-derived neurotrophic factor (BDNF) - TrkB signaling in depression: Biomarker and novel therapeutic target -- Targeting opioid receptors for innovative antidepressant therapies: rediscovering the opioid cure -- Prolactin and somatostatin responses to antidepressant therapy -- The role of vasopressin in anxiety and depression -- Ketamine: the glutamatergic antidepressant and its efficacy -- Acetylcholinergic nicotinic receptors as pharmacological targets for cognitive enhancement: emerging evidence from psychosis populations.-The glutamate mGluR5 receptor as a pharmacological target to enhance cognitive function: emerging evidence from psychosis models -- Corticotropin-releasing factor receptors as a potential target in the developments of antidepressant drugs -- Nitric oxide signaling in depression and antidepressant action -- The role of arrestins in the neuroprotective aspects of antidepressant drugs -- Antidepressant drugs and phosphodiesterases -- Effect of methylphenidate and atomoxetine on development of the brain -- S-Adenosyl-L-methionine for major depressive disorder -- The role of antiepileptic drugs in bipolar depression -- Melatonin and other neuroprotective agents target molecular mechanisms of disease in amyotrophic lateral sclerosis.