Introduction:  Advocating for Transdisciplinary Treatment of Sexual Dysfunction -- Employing a Biopsychosocial Behavioral and Cultural Approach -- Why is Sex Important? -- The Impact of the Environment on Sexual Health -- Multicultural Sensitivity in the Treatment of Sexual Dysfunction -- Anatomy and Physiology of Erection, Ejaculation, and Orgasm -- Urologic and Clinical Evaluation of the Male with Erectile Dysfunction -- Urologic/Clinical Treatment of Erectile Dysfunction -- The Impact of Lifestyle Modification on Erectile Dysfunction -- Erectile Dysfunction in the Setting of Prostate Cancer -- Peyronie's Disease and Other Anatomical Disorders -- The Future of Erectile Dysfunction Therapy I - Implementation of Translational Research -- The Future of Erectile Dysfunction Therapy II - Novel Pharmacotherapy and Innovative Technology -- Underlying Principles in Ejaculatory and Orgasmic Function and Dysfunction in the Male -- Clinical evaluation and treatment of disorders of ejaculation -- Evaluation and Treatment of Orgasmic Dysfunction -- Hypoactive Sexual Desire in Men -- Pelvic Floor Physical Therapy in the Treatment of Sexual Dysfunctions -- The Female Sexual Response: Anatomy and Physiology of Sexual Desire, Arousal, and Orgasm in Women -- Diagnosis of Female Sexual Dysfunction -- The Epidemiology and Diagnosis of Hypoactive Sexual Desire Disorder.  Causes of HSDD:  Situational, depression, drugs, chronic illnesses, and hormonal depletion -- Management of Hypoactive Sexual Desire Disorder (HSDD) -- Diagnosis and Management of Female Sexual Arousal Disorder -- Diagnosis and Management of Female Orgasmic Disorder -- Vaginismus: When Genito-Pelvic Pain /Penetration Disorder Makes Intercourse Seem Impossible -- Diagnosis and Management of Sexual Pain Disorder: Dyspareunia -- New Concepts in the Understanding of Female Sexual Dysfunction -- Female Sexual Dysfunction and Cancer -- Female Sexual Dysfunction and Premature Menopause with focus on women's wording -- Female Sexual Dysfunction and Infertility -- Female Sexual Dysfunction: Impact of the Life Cycle (Pregnancy, Children and Aging) -- It Takes Two to Tango: Evaluation and Treatment of Sexual Dysfunction in the Couple -- Infertility and Sexual Dysfunction (SD) in the Couple -- Couples Therapy and Counseling -- The Intersection of Sexually Transmitted Infection and Sexual Disorders in the Couple -- Epilogue: Cautiously Optimistic For The Future of A Transdisciplinary Sexual Medicine.