Public Health Informatics: an Introduction -- History of Public Health Information Systems and Informatics -- Public Health Informatics in the Larger Context of Biomedical and Health Informatics -- Governmental and Legislative Context for Informatics -- Role of Informatics in Bridging Public and Population Health -- Information Infrastructure to Support Public Health -- Data Sources and Data Tools: Preparing for the Open Data Ecosystem -- Public Health Information Standards -- Privacy and Confidentiality of Public Health Information -- Health Systems Security -- Electronic Health Records: Origination, Adoption, and Progression -- Public Health Analytics and Big Data -- Project Management and Public Health Informatics -- Informatics in Disease Prevention and Epidemiology -- Public Health Laboratories -- The US National Vital Statistics System -- Syndromic Surveillance - a Practical Application of Informatics -- New Means of Data Collection and Accessibility -- Interoperability and Health Information Exchange for Public Health -- Geographic Information Systems -- Public Health Decision Support Systems -- Local and Regional Public Health Informatics -- Public Health Informatics and the American Indian/Alaska Native Populations: Improving Community Health Despite Challenges -- Advancing Informatics Policy and Practice: A State Perspective -- National Public Health Informatics, United States -- Perspectives on Global Public Health Informatics -- Improving immunization through informatics: Perspectives from the BID Initiative Partnership with Tanzania and Zambia -- Public Health Informatics: the Path Forward.