Part 1. Introduction -- Chapter 1. History of Tuberculosis -- Chapter 2. Mycobacterium tuberculosis: the organism, genomics and evolution -- Chapter 3. Pathogenesis and immunology of TB -- Chapter 4. Basic and descriptive epidemiology of TB -- Chapter 5. TB WHO recommended strategies and Global Health perspectives (and exercise/country examples) -- Part 2. Prevention -- Chapter 6. Vaccines -- Chapter 7. Latent TB infection diagnosis and treatment -- Chapter 8. Infection Control (and exercise). Part 3. Diagnosis -- Chapter 9. TB Clinical presentation and differential diagnosis -- Chapter 10. Laboratory diagnosis of TB (including MDR) -- Chapter 11. Radiology in the diagnosis of TB - How to read a chest x-ray -- IV. Treatment -- Chapter 12. Rationale for chemotherapy (and exercise) -- Chapter 13. Anti-TB drugs and adverse events -- Chapter 14. Treatment of drug-susceptible TB -- Chapter 15. Surgery and TB -- Chapter 16. How to design the regimen for drug-resistant TB (and clinical cases) -- Chapter 17. The shorter regimen for MDR-TB -- Chapter 18. Monitoring treatment: clinical and programmatic approach for TB and DR-TB -- Chapter 19. Adherence -- Chapter 20. TB Patient-centred care -- Part 5. Risk factors, risk groups, challenges -- Chapter 21. TB, alcohol, smoking and diabetes. Chapter 22. TB and prisons -- Chapter 23. TB and migration -- Chapter 24. The TB/HIV association -- Chapter 25. Childhood TB -- Chapter 26. Tuberculosis and women (risk factors, pregnancy, access to services and gender issues) -- Chapter 27. TB in the elderly -- Chapter 28. Extra-pulmonary TB -- Chapter 29. Renal and hepatic failure and tuberculosis -- Chapter 30. TB Rehabilitation and palliative care -- Chapter 31. Post TB infections -- Part 6. Public Health -- Chapter 32. The national TB programme: role and functions (and exercise) -- Chapter 33. National TB Strategic Planning (and exercise) -- Chapter 34. Active case finding and hard-to-reach TB groups -- Chapter 35. Managing TB outbreaks in low-incidence settings (and exercise) -- Part 7. Global Health -- Chapter 36. The global TB burden -- Chapter 37. A multi-sectorial approach to tuberculosis control and elimination in the era of the UN Sustainable Development Goals -- Chapter 38. "One Health" approach to zoonotic tuberculosis. The burden of zoonotic tuberculosis in the world -- Chapter 39. Health systems and TB control -- Chapter 40. The global and individual economics of TB -- Part 8. Research -- Chapter 41. An overview of research priorities in TB -- Chapter 42. Priority areas for TB vaccines -- Chapter 43. Priority areas for TB diagnosis -- Chapter 44. Priority areas for latent infection -- Chapter 45. Priority areas for TB treatment -- Chapter 46. Operational Research.