Overview and definition of the fibromyalgia syndrome -- History of fibromyalgia and evolution of nomenclature -- Chronic fatigue - definition and overlap with fibromyalgia -- Chronic pain as a pathogenetic and clinical entity -- Etiology and triggers in the development of fibromyalgia -- Epidemiology of fibromyalgia and chronic pain -- Pharmacological treatment of fibromyalgia -- Complementary and alternative treatments -- Neuromodulation for the treatment of fibromyalgia, including neurofeedback -- Classification, criteria diagnosis -- Psychiatric comorbidity -- Fibromyalgia genetics -- The clinical spectrum of fibromyalgia and overview of approach to treatment -- Functional syndromes as fibromyalgia comorbidities -- Cognitive behavioral treatment and other types of psychotherapy -- Pediatric fibromyalgia -- The neuroscience of fibromyalgia and central sensitization -- Role of the immune system in fibromyalgia -- The autonomic nervous system inn fibromyalgia -- Sleep disorders and management in fibromyalgia and chronic pain -- Assessing disability in fibromyalgia -- Comorbidity of fibromyalgia in non-functional disorders - clinical and research implications -- Cannabinoids in the fibromyalgia syndrome -- Infections and vaccinations -- Fibromyaliga and vaccinations -- Small fiber neuropathy -- Conclusion. .