This book constitutes revised selected papers of the 7th Latin American High Performance Computing Conference, CARLA 2020, held in Cuenca, Ecuador, in September 2020. Due to the COVID-19 pandemic the conference was held in a virtual mode. The 15 revised full papers presented were carefully reviewed and selected out of 36 submissions. The papers included in this book are organized according to the topics on High Performance Computing Applications; High Performance Computing and Artificial Intelligence.