This book constitutes the refereed post-conference proceedings of the 10th International Workshop on Socio-Technical Aspects in Security and Trust, STAST 2020, held as a virtual event, in September 2020. The 8 full papers and 3 short papers presented in this volume were carefully reviewed and selected from 42 submissions and are organized in the following topical sections: personality and behavior; behavior in face of adversaries; smart environments; decentralized systems and digital ledgers; and reflections on socio-technical aspects of security. The Chapter "Statistical Reliability of 10 Years of Cyber Security User Studies" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.