1 Introduction: Problems in Environmental Monitoring and Assessment -- 1 Statistical Methods for Environmental Monitoring and Assessment -- 2 Outline of Case Studies -- 3 Sources of Data and Software -- Acknowledgments -- 2 Modeling Ozone in the Chicago Urban Area -- 1 Introduction -- 2 Data Sources -- 3 Trend Analysis and Adjustment -- 4 Trends from Semiparametric Models -- 5 Trends in Exceedances -- 6 Summary -- Acknowledgments -- References -- 3 Regional and Temporal Models for Ozone Along the Gulf Coast -- 1 Introduction -- 2 Diurnal Variation in Ozone -- 3 Meteorological Clusters and Ozone -- 4 Regional Variation in Ozone -- 5 Summary -- 6 Future Directions -- References -- 4 Design of Air-Quality Monitoring Networks -- 1 Introduction -- 2 Data -- 3 Spatial Models -- 4 Thinning a Small Urban Network -- 5 Adding Rural Stations to Northern Illinois -- 6 Modifying Regional Networks -- 7 Scientific Contributions and Discussion -- References -- 5 Estimating Trends in the Atmospheric Deposition of Pollutants -- 1 Introduction -- 2 Monitoring Data -- 3 Case Studies -- 4 Future Research -- Acknowledgment -- References -- 6 Airborne Particles and Mortality -- 1 Introduction -- 2 Statistical Studies of Particles and Mortality -- 3 An Example: Data from Birmingham, Alabama -- 4 Results for Birmingham -- 5 Comparisons with Other Cities -- 6 Conclusions: Accidental Association or Causal Connection -- References -- 7 Categorical Exposure-Response Regression Analysis of Toxicology Experiments -- 1 Introduction -- 2 The Tetrachloroethylene Database -- 3 Statistical Models for Exposure-Response Relationships -- 4 Computing Software: CatReg -- 5 Application to Tetrachloro ethylene Data -- 6 Conclusions -- 7 Future Directions -- Acknowledgments -- References -- 8 Workshop: Statistical Methods for Combining Environmental Information -- 1 The NISS-USEPA Workshop Series -- 2 Combining Environmental Information -- 3 Combining Environmental Epidemiology Information -- 4 Combining Environmental Assessment Information -- 5 Combining Environmental Monitoring Data -- 6 Future Directions -- References -- A Appendix A: FUNFITS, Data Analysis and Statistical Tools for Estimating Functions Douglas Nychka, Perry D. Haaland, Michael A. O'Connell, Stephen Ellner -- 1 Introduction -- 2 What's So Special About FUNFITS? -- 2.1 An Example -- 3 A Basic Model for Regression -- 4 Thin-Plate Splines: tps -- 4.1 Determining the Smoothing Parameter -- 4.2 Approximate Splines for Large Data Sets -- 4.3 Standard Errors -- 5 Spatial Process Models: krig -- 5.1 Specifying the Covariance Function -- 5.2 Some Examples of Spatial Process Estimates -- Acknowledgments -- References -- B Appendix B: DI, A Design Interface for Constructing and Analyzing Spatial Designs Nancy Saltzman, Douglas Nychka -- 1 Introduction -- 2 An Example -- 3 How DI Works -- 3.1 Network Objects -- 3.2 The Design Editor -- 3.3 User Modifications -- C Appendix C: Workshops Sponsored Through the EPA/NISS Cooperative Agreement -- D Appendix D: Participating Scientists in the Cooperative Agreement.