1 Molecular Aspects of Neurotransmitter Receptors: An Overview -- 1. Receptor Recognition: Ion and Nucleotide Regulation Associated with "Second Messengers" -- 2. Solubilized and Purified Receptors Clarify Synaptic Mechanisms -- 3. Neurotransmitter Uptake Receptors -- 4. References -- 2 Opiate Receptors -- 1. Introduction -- 2. Scope and Limitations of Methods -- 3. Heterogeneity of Opiate Receptors -- 4. Distribution of Opiate Receptors -- 5. Properties of the Opiate Binding Sites -- 6. Isolation of Opiate Receptors -- 7. Assessment of the Pharmacological and Binding Properties of Narcotic Analgesic Drugs -- 8. Excitation Effector Coupling -- 9. Changes in Binding Sites Induced by Drugs or Pathological Conditions -- 10. References -- 3 CNS Dopamine Receptors -- 1. Introduction -- 2. Dopaminergic Agonists and Antagonists and Their Actions -- 3. Anatomy -- 4. Pharmacological Characterization of Dopamine Receptors -- 5. Dopamine Receptors in the Pituitary -- 6. Dopamine Receptors in the Striatum -- 7. Irreversible Modification of Dopamine Receptors -- 8. Solubilization and Isolation of Dopamine Receptors Ill -- 9. Neuroanatomical Localization of Dopamine Receptors in the CNS -- 5. Neostriatum -- 6. Substantia Nigra -- 7. Retina -- 1. Regulation of Dopamine Receptors -- 2. Concluding Comments -- 3. References -- 4 5-Hydroxytryptamine Receptors in Brain -- 1. Introduction -- 2. Serotoninergic Recognition Sites in the CNS -- 3. 5-HT-Sensitive Adenylate Cyclase -- 4. Mechanism of Regulation of Serotonin Receptors -- 5. Conclusions -- 6. References -- 5 Receptors for Amino Acid Transmitters -- 1. Introduction -- 2. GAB A Receptors -- 3. Glycine Receptors -- 4. Other "Inhibitory Amino Acids" -- 5. Excitatory Amino Acids -- 6. Summary -- 7. References -- 6 The Nature of Muscarinic Receptor Binding -- 1. Introduction -- 2. The Binding of Antagonists -- 3. The Binding of Agonists -- 4. Regulation of Muscarinic Receptors by Guanine Nucleotides -- 5. The Influence of Sulfhydryl Reagents on Muscarinic Receptor Binding -- 6. Ionic Perturbation of Muscarinic Receptor Binding -- 7. Regulation of Antagonist Binding by Dopaminergic Agonists -- 8. Conclusion -- 9. References -- 7 Benzodiazepine Receptors -- 1. Introduction -- 2. Biochemical Characteristics of Benzodiazepine Receptor Binding -- 3. BZ Receptor Solubilization -- 4. Occurrence of BZ Receptors -- 5. Structural Selectivity of BZ Receptors -- 6. BZ Receptor Binding in Vivo -- 7. Multiple Brain BZ Receptors -- 8. BZ Receptors and GABA -- 9. Miscellaneous Modulators -- 10. In Vivo BZ Receptor Modulation -- 10.1. Subchronic Treatment with Benzodiazepines -- 10.2. Barbiturates -- 10.3. Ethanol -- 10.4. Diphenylhydantoin -- 10.5. Seizures and Other "Stress" -- 11. Endogenous Ligands? -- 12. Radioreceptor Assay -- 13. References -- 8 Histamine Receptors in Brain -- 1. Introduction -- 2. Classification of Histamine Receptors -- 3. The Histamine Hi-Receptor -- 4. The Histamine H2-Receptor -- 5. Psychotropic Drugs and Histamine Receptors -- 6. References.