Cover; Title page; Copyright Page; Contents; Contributors; Chapter One -- Compartmentalization and Regulation of Sulfate Assimilation Pathways in Plants ; Abstract; 1 Introduction; 2 Sulfate Transport Systems; 2.1 Molecular Cloning of Sulfate Transporter; 2.2 Sulfate Uptake in Roots; 2.2.1 Transporters for Sulfate Uptake in Roots; 2.2.2 Regulation of Sulfate Uptake; 2.3 Sulfate Distribution in Plants; 2.3.1 Root-to-Shoot Transport of Sulfate; 2.3.2 Source-to-Sink Transport of Sulfate and Sulfur Metabolites; 2.3.3 Intracellular Transport of Sulfate; 3 Sulfate Assimilation.

3.1 Metabolic Pathway Compartmentalization and Regulation3.1.1 APS and PAPS Biosynthetic Pathways; 3.1.2 Sulfur Metabolic Flux Partitioning and Regulation; 3.2 Plastid-Cytosol Metabolic Pathway Integration; 3.2.1 PAPS Transport and Metabolism; 3.2.2 Synergy in Metabolic Flux Regulation; 4 Conclusions and Future Perspectives; Acknowledgments; References; Chapter Two -- Insight Into the Role of Long Noncoding RNA in Cancer Development and Progression ; Abstract; 1 Introduction; 1.1 Molecular Mechanisms of lncRNA; 1.2 Cancer-Associated Signaling Pathways.

2 Roles of lncRNA During Cancer Development2.1 Chromosomal Instability; 2.2 DNA Damage Response; 2.3 Virus-Induced Carcinogenesis; 2.4 Carcinogen Stimulation; 3 Cancer Cell Survival; 3.1 Cancer Metabolism; 3.2 Radiation and Oxidative Stress; 3.3 Hypoxia; 4 LncRNA in Cancer Stem Cell; 4.1 Stemness Features; 4.2 Renewal; 4.3 Transformation of Cancer Stem Cell; 5 Insight of Novel lncRNA Roles in Cancer; 5.1 Immunity; 5.2 Cancer Microenvironment; 6 Diagnostic and Prognostic Value of lncRNAs; 7 Concluding Remarks; Acknowledgment; References.

Chapter Three -- Endogenous Mechanisms of Cardiac Regeneration Abstract; 1 Introduction; 2 Endogenous Cellular Sources for Cardiac Regeneration; 2.1 Cardiac Stem and Progenitor Cells; 2.1.1 Identification of Cardiac Stem and Progenitor Cells; 2.1.2 Regenerative Capacity of c-Kit+ Cardiac Stem Cells; 2.1.3 Genetic Fate-Mapping of Endogenous Cardiac Stem Cells; 2.2 Cardiomyocytes; 2.2.1 Adult Zebrafish Cardiomyocytes; 2.2.2 Proliferative Capacity of Mouse Cardiomyocytes; 2.2.3 Evidence for Cardiomyocyte Renewal in Adult Humans; 2.3 Transdifferentiation.

2.3.1 Epicardial to Myocardial Transdifferentiation2.3.2 Atrial-to-Ventricular Muscle Lineage Conversion; 2.3.3 Contributions by Noncardiac Stem Cells; 3 Molecular Mechanisms Limiting Cardiac Regeneration; 3.1 Postnatal Changes Inducing Cardiomyocyte Cell Cycle Arrest; 3.1.1 Postnatal Induction of Global DNA Methylation; 3.1.2 Cell Cycle Regulation by Transcription Factor Meis1; 3.1.3 Loss of Centrosome Integrity and Cell Cycle Arrest; 3.2 miRNAs That Suppress Cardiomyocyte Proliferation; 3.2.1 miR-15 Family; 3.2.2 miR-133 Family; 3.2.3 miR-99/100 Family.