Cover; Title page; Copyright Page; Contents; Contributors; Preface; Chapter One -- Competition for Manganese at the Host-Pathogen Interface ; Abstract; 1 Introduction; 2 Imposition of Manganese Starvation by the Host; 3 Bacterial Adaptation to Manganese Limitation; 4 Impact of Manganese Limitation on Invading Microbes; 5 Conclusions and Broader Impacts; References; Chapter Two -- Microbial Virulence and Interactions With Metals ; Abstract; 1 Iron; 1.1 Sequestering of Iron by Bacteria; 2 Copper; 2.1 Plasmid-Borne Resistance; 2.2 Copper-Binding Siderophores; 3 Manganese; 4 Zinc; References.

Chapter Three -- Virulence Program of a Bacterial Plant Pathogen: The Dickeya Model Abstract; 1 Introduction; 2 Dickeya Ecology; 3 The Virulence Determinants of D. Dadantii; 3.1 The Effectors of Type-I and Type-II Secretion Systems; 3.2 The Hrp Type-III Secretion System and Its Substrates; 3.3 The Siderophores and Iron Metabolism; 4 Plant-Pathogen Interaction Process; 4.1 Adhesion to Plant Surface and Entry Into Apoplast; 4.2 Role of Multiple Efflux Pumps for Surviving in the Plant Apoplast; 4.3 Adaptation to the Acidic Environment of Apoplast and to Plant Antimicrobial Peptides.

4.4 Adaptation to Anaerobiosis Conditions in Plant Tissue4.5 Adaptation to Reactive Oxygen Species Produced by Plant in Response to Infection; 4.6 Adaptation to Osmotic Stress Resulting From Plant Cell Lysis; 5 Regulatory Mechanisms Coordinating the Virulence Program; 5.1 Regulatory Network Coordinating Multiple Virulence Factor Expression; 5.2 NAPs and Chromosome Dynamics; 6 Concluding Remarks; References; Chapter Four -- Metabolism and Virulence Strategies in Dickeya-Host Interactions ; Abstract; 1 Introduction; 2 The Dickeya Virulence Strategy.

2.1 Plant Colonization and the Infectious Phases2.2 Pectate Lyases and Plant Cell Wall Degradation; 3 The Dickeya Catabolic Capacities; 3.1 What Information From the Genome?; 3.2 The Transcriptomic Approaches; 3.3 Contribution of Metabolomics; 4 The Major Carbon Sources Assimilated by Bacteria in Plant Tissues; 4.1 Utilization of the Plant Soluble Sugars; 4.2 Utilization of Sugars Derived From Pectic Polysaccharides; 5 The Regulators Coordinating Virulence and Metabolism; 5.1 The Pectin Sensor KdgR; 5.2 The cAMP Receptor Protein (Crp) for Preferential Sugar Utilization.

5.3 The GacA/GacS Two-Component System and Rsm Posttranscriptional Regulation5.4 Other Regulatory Systems; 6 Concluding Remarks; Acknowledgments; References; Chapter Five -- Multidrug Efflux Pumps in the Genus Erwinia: Physiology and Regulation of Efflux Pump Gene Expression ; Abstract; 1 Introduction; 1.1 Plant-Pathogen Interaction: An Overview; 2 Bacterial efflux pumps; 2.1 Types; 2.2 Occurrence; 3 Efflux pumps in Erwinia; 3.1 RND Efflux Pumps; 3.1.1 Acr (Acriflavine) Efflux System; 3.1.2 MdtABCD and MdtUVW Efflux Pumps; 3.2 MFS Efflux Pumps; 3.2.1 EmrAB Efflux Pump; 3.2.2 YceE Efflux Pump.