Front Cover -- Advances in Genetics -- Serial Editors -- Advances in Genetics -- Contents -- Copyright -- CONTRIBUTORS -- One -- Fungal Light Sensing at the Bench and Beyond -- 1. INTRODUCTION -- 2. FUNGAL LIGHT SENSING: OF PRISMS AND PROTEINS -- 2.1 Blue Light: Making Fungi LOV and CRY -- 2.1.1 The White Collar Orthologs -- 2.1.1.1 White Collar-1 of Neurospora crassa: A Model of Induction -- 2.1.1.2 LreA of Aspergillus nidulans: A Model of Repression -- 2.1.2 VIVID and ENVOY: Small LOV Domain Proteins with Big Roles -- 2.1.3 Cryptochromes: "New" Functions for an Ancient Protein -- 2.2 Red Light: Phytochromes Under the Light -- 2.2.1 FphA in the Nucleus -- 2.2.2 FphA in the Cytoplasm -- 2.3 Green Light: A Story of Opsin Evolutionary and Functional Elusiveness -- 2.4 Concluding Remarks -- 3. PHOTOBIOLOGY IN INDUSTRIALLY IMPORTANT FUNGI -- 3.1 Light Regulation of Primary Metabolism: Food for Thought ... and Fuel -- 3.2 Light Regulation of Secondary Metabolism: A Tale of Toxins -- 4. PHOTOBIOLOGY IN AGRICULTURALLY IMPORTANT FUNGI -- 4.1 Regulation of Virulence of Plant Pathogenic Fungi by Light and/or Photosensory Pathways -- 4.1.1 Light Induction of Fungal Virulence -- 4.1.2 Light Suppression of Virulence -- 4.1.3 Circadian Control over the Host-Pathogen Interaction -- 4.2 Light as an Agent to Promote Sporulation and Robustness of Biocontrol Fungi -- 5. PHOTOBIOLOGY IN MEDICALLY IMPORTANT FUNGI -- 5.1 Do the White Collar Proteins Play a Conserved Role in Human Fungal Pathogenesis? -- 5.2 Can Light Itself Augment Fungal Virulence? -- 6. IN CONCLUSION: LET THERE BE LIGHT! -- ACKNOWLEDGMENTS -- REFERENCES -- Two -- Advances in Dyslexia Genetics-New Insights Into the Role of Brain Asymmetries -- 1. INTRODUCTION -- 1.1 History of Difficulty with Reading -- 1.2 Dyslexia Definitions -- 1.3 Comorbidities With Other Conditions.

2. MANY THEORIES TO EXPLAIN DYSLEXIA -- 2.1 The Phonological Theory -- 2.2 Slow Temporal Processing -- 2.3 Attention -- 2.4 Endophenotypes -- 2.5 Impaired Auditory Processing -- 2.6 Impaired Visual Processing -- 2.7 The Visual Magnocellular System -- 2.8 The Magnocellular Perineuronal Net -- 2.9 Magnocellular Impairments in Dyslexia -- 2.10 Dyslexia Brain Differences and Laterality -- 3. DYSLEXIA HERITABILITY -- 3.1 Phenotype Definition for Genetic Studies -- 3.2 Candidate Genes -- 3.3 GWAS for Dyslexia or Reading-Related Traits -- 3.4 GWAS for Other Reading-Related Traits -- 3.5 Dyslexia Genome-Wide Association Studies in the Future -- 3.6 Other Genome-Wide Approaches: Copy Number Variant Studies -- 3.7 Copy Number Variant Studies for Dyslexia-Related Phenotypes -- 3.8 Next-Gen Studies -- 4. FROM STATISTICAL VALUES TO DISORDER BIOLOGY -- 4.1 Cilia Biology and Neurodevelopment -- 4.2 Dyslexia Candidate Genes and Cilia -- 4.2.1 DYX1C1 -- 4.2.2 DCDC2 -- 4.2.3 Transmembrane Proteins: KIAA0319 and ROBO1 -- 4.2.4 Rare Variants -- 4.3 Cilia, Handedness, and Dyslexia -- 5. COMPLEX TRAIT, COMPLEX GENETICS -- 6. CONCLUDING REMARKS -- ACKNOWLEDGMENTS -- REFERENCES -- Three -- Genetics of Schizophrenia: Historical Insights and Prevailing Evidence -- 1. INTRODUCTION -- 2. GENETICS OF SCHIZOPHRENIA -- 2.1 From Linkage Studies to Genome-Wide Association Studies -- 2.1.1 Into Genome-Wide Association Studies of Common Variants -- 2.2 Insights From Rare and De Novo Mutation Events -- 3. EPIGENETIC RISK FACTORS FOR SCHIZOPHRENIA -- 3.1 Epigenetics -- 3.2 Epigenetics in Schizophrenia -- 3.2.1 Schizophrenia Genomic Studies and Their Epigenetic Implications -- 3.2.2 Epigenetic/Epigenomic Studies and Their Schizophrenia Implications -- 3.2.3 Epigenome-Wide Association Studies for Schizophrenia -- 4. DISCUSSION -- 4.1 Schizophrenia Genetics -- 4.2 Schizophrenia Epigenetics.

4.3 Concluding Remarks -- REFERENCES -- Four -- The Functionality and Evolution of Eukaryotic Transcriptional Enhancers -- 1. INTRODUCTION -- 2. THE IDENTIFICATION OF ENHANCERS -- 2.1 Phylogenetic Footprinting -- 2.2 ChIP-Seq -- 2.3 ATAC-Seq -- 2.4 Chromosome Conformation Capture Methods: 3C, 4C, 5C, and Hi-C -- 2.5 TALEs and CRISPR -- 3. ENHANCER FUNCTIONALITY -- 3.1 Enhanceosomes Versus Billboards -- 3.2 Transcription Factor Binding Site Affinity -- 3.3 Enhancing From Distance -- 3.4 Shadow Enhancers -- 3.4.1 Shadow Enhancers in Drosophila -- 3.4.2 Shadow Enhancers in Vertebrates -- 3.5 Super Enhancers -- 3.5.1 Novel Regulatory Elements or Clusters of Classical Enhancers? -- 3.6 Enhancing in trans -- 3.6.1 Cytokine Genes -- 3.6.2 Transvection in Drosophila -- 4. ENHANCER EVOLUTION -- 4.1 Enhancer Conservation -- 4.2 Divergent Enhancers -- 4.3 Coevolution and Developmental Systems Drift -- 4.4 The Molecular Evolution of Enhancers -- 4.5 Cis-Regulatory Evolution and Phenotypic Diversification -- 4.5.1 Evolution of New Enhancers via Gene Duplication -- 4.5.2 The Genetic Basis of Phenotypic Evolution -- 4.5.3 Wing Spot Pigmentation Pattern Evolution in Drosophila -- 4.5.4 Trichome Pattern Evolution and Shavenbaby -- 4.5.5 Skeletal Changes in Vertebrates -- 4.5.6 Enhancers Can Evolve in Different Ways to Facilitate Phenotypic Change -- 4.5.7 Temporal Order of Mutations? -- 5. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- K -- L -- M -- N -- O -- P -- R -- S -- T -- V -- W -- Z -- Back Cover.