Nonmotor Parkinson's : the Many Hidden Faces.
Başlık:
Nonmotor Parkinson's : the Many Hidden Faces.
ISBN:
9780128137093
9780128137086
Personal Author:
Yayın Bilgileri:
San Diego : Elsevier Science, 2017.
Fiziksel Tanımlama:
1 online resource (796 pages)
Series:
International Review of Neurobiology ; v. Volume 133
International review of neurobiology.
Genel Not:
Further Reading.
Contents:
Front Cover; Nonmotor Parkinson's: The Hidden Face: The Many Hidden Faces; Copyright; Contents; Contributors; Prefaces; Message from Professor Günther Deuschl, Europoean Academy of Neurology; Message from Professor Christopher G. Goetz, International Parkinson's and Movement Disorders Society; The Editors Words; Section 1: Nonmotor Symptoms: The Hidden Face of Parkinson's; Chapter One: The Status of ""Nonmotor"" Features of the Malady in an Essay on the Shaking Palsy (1817); 1. Introduction; 2. Clinical Features of the Shaking Palsy; 3. ""Nonmotor"" Components of the Shaking Palsy.
4. ConclusionReferences; Chapter Two: Neuropathology of Nonmotor Symptoms of Parkinson's Disease; 1. Introduction; 2. Preclinical PD; 2.1. Incidental Lewy Body Disease; 3. Parkinson's Disease; 4. Circadian System Disorders; 4.1. Rapid Eye Movement Sleep Disorder; 5. Olfactory Dysfunction/Hyposmia; 6. Autonomic Dysfunction; 6.1. GI Disorders; 6.2. Genitourinary Symptoms; 6.3. Cardiovascular Symptoms; 7. Visual Dysfunctions; 8. Sensory Disturbances and Pain; 9. Neuropsychiatric Symptoms; 9.1. Mood Disorders; 10. Cognitive Impairment; 10.1. Mild Cognitive Impairment; 11. Dementia; 12. Psychosis.
13. Conclusions and Further OutlookAcknowledgments; References; Chapter Three: Nonmotor Symptoms in Experimental Models of Parkinson's Disease; 1. Introduction; 2. Experimental Models of PD and the Occurrence of Nonmotor Symptoms; 3. Relating NMS in Experimental Models of PD to Pathophysiology; 3.1. Altered Olfaction; 3.2. Altered Cardiovascular Function; 3.3. Alterations in Sleep; 3.4. Alteration in Gastrointestinal Tract; 3.5. Alterations in Bladder Functions; 3.6. Alterations in Mood and Cognition; 3.6.1. Anxiety; 3.6.2. Depression; 3.6.3. Apathy; 3.6.4. Attention and Memory.
3.7. Alteration in Perception, Psychosis, and Vision4. Conclusions and Observations; References; Chapter Four: The Epidemiology of Nonmotor Symptoms in Parkinson's Disease (Cohort and Other Studies); 1. Background: The Concept of ""Holistic"" Nonmotor Symptoms in Parkinson's Disease and Difficulties With Data Capture; 2. Comprehensive Clinical Assessment of NMS in PD; 3. Holistic Assessment of Prevalence of NMS in PD; 3.1. NMS in De Novo and Early PD Patients and Cohorts; 3.2. Cluster Analysis in De Novo PD Patients; 4. NMS Prevalence in Treated PD Cohorts; 5. Studies With NMSS in PD.
6. Age, Age of Onset, Disease Duration, and Prevalence of NMS in PD7. Conclusions; References; Chapter Five: Genes and Nonmotor Symptoms in Parkinson's Disease; 1. Introduction; 2. Genetic Links to Individual NMS in PD; 2.1. Genetic Risk Factors for Cognitive Impairment; 2.2. Genetic Risk Factors for Depression; 2.3. Genetic Risk Factors for Psychosis; 2.4. Genetic Risk Factors for Impulse Control Disorders; 2.5. Genetic Risk Factors for Sleep Disorders; 2.6. Genetic Risk Factors for Pain; 2.7. Genetic Risk Factors for Olfactory Dysfunction; 3. Conclusions; Acknowledgments; References.
Abstract:
Annotation Non-motor Parkinson's: The Hidden Face, Volume 133, the first part of the latest volume in the International Review of Neurobiology series, is an up-to-date, comprehensive textbook addressing the non-motor aspects of Parkinson's disease, a key unmet need. Chapters in this new release include topics such as The hidden face of Parkinson's, JP and non-motor symptoms, Parkinson's: a complex non-motor disease, Neuropathology of NMS of PD, Neurophysiology and animal models related to NMS in PD, Epidemiology of NMS in PD (cohort studies), Genes and NMS in PD, NMS in genetic forms of PD, and Imaging the NMS in PD. Including practical tips for non-specialists and clinical algorithms, this book contains contributions from over 40 opinion leaders in the field of movement disorders, covering the topic from laboratory, to bedside, to caregiver. Presents a comprehensive textbook on the non motor aspects of Parkinson's diseaseIncludes practical tips and clinical algorithms, and is the only textbook to bring a holistic approach Contains contributions from over 40 global opinion leaders in the field of movement disordersProvides special chapters on exercise, personalized medicine, osteoporosis, genetics, treatment aspects and nutrition.
Local Note:
Elsevier
Added Author:
Elektronik Erişim:
Full Text Available From Elsevier e-Books
Dil:
English