Bioenergetics and Thermodynamics: Model Systems Synthetic and Natural Chelates and Macrocycles as Models for Biological and Pharmaceutical Studies
题名:
Bioenergetics and Thermodynamics: Model Systems Synthetic and Natural Chelates and Macrocycles as Models for Biological and Pharmaceutical Studies
ISBN:
9789400990357
版:
1st ed. 1980.
PRODUCTION_INFO:
Dordrecht : Springer Netherlands : Imprint: Springer, 1980.
物理描述:
484 p. online resource.
系列:
Nato Science Series C:, Mathematical and Physical Sciences ; 55
内容:
Bioenergetics and Thermodynamics. Aims and Methodology of the School -- Design of Peptide Molecules to Mimic the Metal Binding Sites of Proteins -- Calorimetry and Biology -- Bioinorganic Chemistry of Nickel -- Design and Synthesis of Ligands -- Holes, Handedness, Handles, and Hopes: Meeting the Requirements of Primary Binding, Chirality, Secondary Interactions and Functionality in Enzyme Analogues -- Testing of Ligands -- Calorimetric Techniques to Study Proton-Ligand and Metal-Ligand Interactions -- Structural and Energetic Aspects of Metal-Ligand Binding -- Transport of Metal Ions by Liquid Membranes Containing Macrocyclic Carriers -- Enthalpy, Free-Energy, and Entropy Data for Structure-Activity Relationships in Acids and Bases -- Potentiometric and Spectroscopic Determination of Equilibrium Constants -- Experimental Data in Chemical and Biological Systems at Equilibrium -- What Concentration Scale? What Standard State? What Species are Present? -- Treatment and Analysis of Equilibrium Data by Computers -- Mixed Complexes -- Kinetics and Thermodynamics of Enzyme Action and Regulation -- Computer Models of Biological Systems -- Membranes, Alkali Metals and Transfer -- Synthetic Solvent-Polymeric Membranes and Their Transport Characteristics -- Macrocycles and Cation Selectivity -- Selectivity of Membranes Towards Ions and Molecules -- Transport Phenomena across Solid and Liquid Membranes -- Carriers and Channels in Artificial and Biological Membranes -- Lipid Bilayer Electrochemistry and -Role of the Carriers -- The Lipid Bilayer: A Model System for Biological Membranes -- Differential Scanning Calorimetry. Processes Involving Proteins -- Recent Advances in Biochemical Calorimetry -- Interpretation of Calorimetric Data from Cooperative Systems -- Selective Complexation of Ammonium and Guanidinium Salts by Synthetic Receptor Molecules -- Dynamical Aspects of Small-Molecule Protein Interaction -- Molecular Receptors, Carriers and Catalysts: Design, Scope and Prospects -- Metal Ions in Biological Systems -- Metal Ion - Protein Interactions in Solutions -- Final Comments -- Contributing authors.
主题词汇:
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附加团体著者:
语言:
英文