Nature Immunology, ranked first out of more than 100 primary immunology research journals, brings together the most significant immunology research from every discipline. Nature Immunology's scope is broad, covering all areas of immunology, including (but not limited to) innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity and tumor immunology, microbial immunopathology and transplantation. By presenting research that provides fundamental insight into the working of the immune system, Nature Immunology communicates the most significant and influential advances to a broad audience.