Metabolic aspects of aging
题名:
Metabolic aspects of aging
ISBN:
9780128096239
版:
First edition.
PRODUCTION_INFO:
London, United Kingdom : Elsevier Ltd. : Academic Press, 2018.
物理描述:
1 online resource
系列:
Progress in molecular biology and translational science ; volume 155
Progress in molecular biology and translational science ; v. 155.
内容:
Cover; Title page; Copyright page; Contents; Contributors; Preface; Chapter one -- Longevity, Metabolic Disease, and Community Health; Abstract; 1 Introduction; 2 Longevity and population trends; 3 Obesity, metabolic syndrome, and aging; 4 Community health and healthy aging; 5 Social determinants of health and aging; 6 Culture and aging; References; Further reading; Chapter two -- Metabolic Aspects of Aging; Abstract; 1 Introduction; 2 CR from yeast to primates; 3 CALERIE study; 4 Fasting and fasting mimicking diet; 5 Protein restriction; 6 Circadian regulation and CR.
7 CR-mimicking interventions on healthspanReferences; Chapter three -- Obesity, Metabolism, and Aging: A Multiscalar Approach; Abstract; 1 Introduction: obesity, aging, and metabolism; 2 Scaling Out: life-history theory; 3 Our hunter-gatherer past; 4 The sugar explosion; 5 The socionomics of aging and metabolism; 6 Conclusions; References; Chapter four -- The Intersection of Curandismo and Western Medicine and Their Epidemiological Impact for Aging Mexican Americans; Abstract; 1 Introduction; 2 Background; 3 Diabetes; 4 Menopause; 5 Dementia; References; Further reading.
Chapter five -- The Necessity of Active Muscle Metabolism for Healthy Aging: Muscular Activity Throughout the Entire DayAbstract; 1 Sedentary time equals muscular inactivity; 2 The goal is to replace as much sedentary time as possible with an equal amount of safe and effective muscular activity throughout the day; 2.1 For Individuals to Age Optimally; 2.2 For Workplace Wellness and Other Programs to be Successful in Preventing Unnecessary Disease; 3 We have reached a point in human history where the ubiquitous act of sitting in a chair has surpassed sleeping as the most abundant behavior.
4 There are many detrimental effects directly caused by many hours per day of muscular inactivity, regardless of age5 The metabolic rate of muscle is determined by whether or not there are ongoing acute periods of contractile activity or muscular inactivity, regardless of age; 6 When active, muscle in elderly people or animals retains its ability to display healthy metabolic responses; 7 The tenets of inactivity physiology for promoting healthy aging; 8 In summary, the direct causes of unhealthy versus healthy aging with respect to metabolism are often rooted in muscle physiology.
9 Concluding statementsAcknowledgments; References; Further reading; Chapter six -- Dwarf Mice and Aging; Abstract; 1 Introduction; 2 Adipose tissue; 3 Quality versus quantity: divergent role of fat in long-living animals; 4 MicroRNA (miRNA) and healthy aging; 5 Energy metabolism; 6 Surgical removal of brown adipose tissue in Ames dwarf mice; 7 Early-life interventions; 8 Review summary; Acknowledgments; References; Chapter seven -- Cellular Metabolism and Aging; Abstract; 1 Introduction; 2 Mitochondria and aging; 2.1 ROS Theory of Aging; 2.2 Mitochondrial Aging; 3 Proteostasis network.
摘要:
Metabolic Aspects of Aging, Volume 155, the latest release in the Progress in Molecular Biology and Translational Science series seeks to provide the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series includes in-depth knowledge on the molecular, biological aspects of organismal physiology and function, with this release including chapters on Longevity, Metabolic Disease and Community Health, the Metabolic Aspects of Aging, Obesity, Metabolism, and Aging: A Multiscalar Approach, The Intersection of Curandismo and Western Medicine and Their Epidemiological Impact for Aging Mexican Americans, and more.
本地注释:
Elsevier
附加著者:
语言:
英文